Трахтманн Н.В., к.б.н., старший научный сотрудник

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Трахтманн Н.В.

к.б.н., старший научный сотрудник

Старший научный сотрудник лаборатории молекулярно-генетических и микробиологических методов, отдел перспективных исследований, ФИЦ КазНЦ РАН

PhD в биологии
hi=10 (Scopus/WoS)

количество публикаций 22 (Scopus/WoS)
https://orcid.org/0000-0002-9441-409X

Образование:

1988-1993 г. кафедра генетики КГУ им.В.И. Ульянова-Ленина

1993-1996 г. Пущинский ГУ, аспирантура

Область научных интересов: генетика микроорганизмов, молекулярная биология, генная инженерия, биотехнология.

Тел. +7 905 0236694

E-mail:  n.trahtman@knc.ru

Адрес: 420059, г.Казань, ул. Оренбургский тракт, д.20А, ком.305

  1. Kholod, N. S.; Pan’kova, N. V.; Maĭorov, S. G.; Krutilina, A. I.; Shliapnikov, M. G.; Ksenzenko, V. N.; Kiselev, L. L. (1996): Vliianie ionov Mg2+ i Ca2+ na aminoatsilirovanie transkriptov genov tRNK(Phe) bakteriofaga T5 i Escherichia coli. In: Molekuliarnaia biologiia 30 (5), S. 1066–1075.
  2. Kholod, N. S.; Pan’kova, N. V.; Mayorov, S. G.; Krutilina, A. I.; Shlyapnikov, M. G.; Kisselev, L. L.; Ksenzenko, V. N. (1997): Transfer RNA(Phe) isoacceptors possess non-identical set of identity elements at high and low Mg2+ concentration. In: FEBS letters 411 (1), S. 123–127. DOI: 10.1016/s0014-5793(97)00608-x.
  3. Pan’kova, N. V.; Karamyshev, A. L.; Shliapnikov, M. G.; Presich, A. N.; Ksenzenko, V. N. (1998): Amber-supressornye tRNK bakteriofaga T5: konstruirovanie genov i opredelenie éffektivnosti supressii in vivo. In: Molekuliarnaia biologiia 32 (6), S. 1004–1012.
  4. Validov, S. Z., Pankova, N.V., Kozlova, E.V., Kuzmin, N.P., Klimenko, V.V. & Boronin, A.M. 1998. Rapid identification of Lactobacillus plantarum by RAPD-PCR. Microbiology 67: 317−322.
  5. Kalebina, T. S.; Laurinavichyute, D. K.; Shevelev, A. B.; Fominov, G. V.; Levitin, E. I.; Alekseeva, O. V. et al. (1998): Purification and characterization of P33 protein of Candida utilis homologous to bgl2p of Saccharomyces cerevisiae; comparative analysis of the role of these proteins in molecular organization of the yeast cell walls. In: Biochemistry. Biokhimiia 63 (12), S. 1419–1423.
  6. Heiss, Gesche; Hofmann, Klaus W.; Trachtmann, Natalie; Walters, Dana M.; Rouvière, Pierre; Knackmuss, Hans-Joachim (2002): npd gene functions of Rhodococcus (opacus) erythropolis HL PM-1 in the initial steps of 2,4,6-trinitrophenol degradation. In: Microbiology (Reading, England) 148 (Pt 3), S. 799–806. DOI: 10.1099/00221287-148-3-799.
  7. Heiss, Gesche; Trachtmann, Natalie; Abe, Yoshikatsu; Takeo, Masahiro; Knackmuss, Hans-Joachim (2003): Homologous npdGI genes in 2,4-dinitrophenol- and 4-nitrophenol-degrading Rhodococcus spp. In: Applied and environmental microbiology 69 (5), S. 2748–2754. DOI: 10.1128/AEM.69.5.2748-2754.2003.
  8. Albermann, Christoph; Trachtmann, Natalie; Sprenger, Georg A. (2010): A simple and reliable method to conduct and monitor expression cassette integration into the Escherichia coli chromosome. In: Biotechnology journal 5 (1), S. 32–38. DOI: 10.1002/biot.200900193.
  9. Bongaerts, Johannes; Esser, Simon; Lorbach, Volker; Al-Momani, Lóay; Müller, Michael A.; Franke, Dirk et al. (2011): Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis. In: Angewandte Chemie (International ed. in English) 50 (34), S. 7781–7786. DOI: 10.1002/anie.201103261.
  10. Rodrigues, André L.; Trachtmann, Nathalie; Becker, Judith; Lohanatha, Ananta F.; Blotenberg, Jana; Bolten, Christoph J. et al. (2013): Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein. In: Metabolic engineering 20, S. 29–41. DOI: 10.1016/j.ymben.2013.08.004.
  11. Trachtmann, Natalia; Alvarez Fong, Karla Fernanda; Guitart Font, Emma; Sprenger, Georg A. (2016): Construction of chromosomally encoded lacZ and gfp reporter strains of Escherichia coli for the study of global regulation of metabolism. In: Engineering in Life Sciences 16 (7), S. 675–681. DOI: 10.1002/elsc.201600056.
  12. Tröndle, Julia; Trachtmann, Natalia; Sprenger, Georg A.; Weuster-Botz, Dirk (2018): Fed-batch production of l-tryptophan from glycerol using recombinant Escherichia coli. In: Biotechnology and bioengineering 115 (12), S. 2881–2892. DOI: 10.1002/bit.26834.
  13. Mohammadi Nargesi, Behrouz; Trachtmann, Natalie; Sprenger, Georg A.; Youn, Jung-Won (2018): Production of p-amino-L-phenylalanine (L-PAPA) from glycerol by metabolic grafting of Escherichia coli. In: Microbial cell factories 17 (1), S. 149. DOI: 10.1186/s12934-018-0996-6.
  14. Sánchez-Moreno, Israel; Trachtmann, Natalia; Ilhan, Sibel; Hélaine, Virgil; Lemaire, Marielle; Guérard-Hélaine, Christine; Sprenger, Georg A. (2019): 2-Ketogluconate Kinase from Cupriavidusnecator H16: Purification, Characterization, and Exploration of Its Substrate Specificity. In: Molecules (Basel, Switzerland) 24 (13). DOI: 10.3390/molecules24132393.
  15. Khusainov, Iskander; Fatkhullin, Bulat; Pellegrino, Simone; Bikmullin, Aydar; Liu, Wen-Ti; Gabdulkhakov, Azat et al. (2020): Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach. In: Nature communications 11 (1), S. 1656. DOI: 10.1038/s41467-020-15517-0.
  16. Tröndle, Julia; Schoppel, Kristin; Bleidt, Arne; Trachtmann, Natalia; Sprenger, Georg A.; Weuster-Botz, Dirk (2020): Metabolic control analysis of L-tryptophan production with Escherichia coli based on data from short-term perturbation experiments. In: Journal of biotechnology 307, S. 15–28. DOI: 10.1016/j.jbiotec.2019.10.009.
  17. Schoppel, Kristin; Trachtmann, Natalia; Mittermeier, Fabian; Sprenger, Georg A.; Weuster-Botz, Dirk (2021): Metabolic control analysis of L-tryptophan producing Escherichia coli applying targeted perturbation with shikimate. In: Bioprocess and biosystems engineering 44 (12), S. 2591–2613. DOI: 10.1007/s00449-021-02630-7.
  18. Schoppel, Kristin; Trachtmann, Natalia; Korzin, Emil J.; Tzanavari, Angelina; Sprenger, Georg A.; Weuster-Botz, Dirk (2022): Metabolic control analysis enables rational improvement of E. coli L-tryptophan producers but methylglyoxal formation limits glycerol-based production. In: Microbial cell factories 21 (1), S. 201. DOI: 10.1186/s12934-022-01930-1.
  19. Jayaraman, Kumaresan; Trachtmann, Natalia; Sprenger, Georg A.; Gohlke, Holger (2022): Protein engineering for feedback resistance in 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. In: Applied microbiology and biotechnology 106 (19-20), S. 6505–6517. DOI: 10.1007/s00253-022-12166-9.
  20. Bikmullin, Aydar G.; Fatkhullin, Bulat; Stetsenko, Artem; Gabdulkhakov, Azat; Garaeva, Natalia; Nurullina, Liliia et al. (2023): Yet Another Similarity between Mitochondrial and Bacterial Ribosomal Small Subunit Biogenesis Obtained by Structural Characterization of RbfA from S. aureus. In: International journal of molecular sciences 24 (3). DOI: 10.3390/ijms24032118.
  21. Trachtmann N, Bikmullin A, Validov S, Sprenger GA. Escherichia coliReporter Strains Allow for the In Vivo Evaluation of Recombinant Elongation Factor Protein (EF-P). Applied Microbiology. 2024; 4(3):1335-1347. https://doi.org/10.3390/applmicrobiol4030092
  22. Frolov M, Kungurov GA, Valiakhmetov EE, Gogov AS, Trachtmann NV, Validov SZ. Construction of the Pseudomonas putidaStrain with Low Motility and Reduced Biofilm Formation for Application in Fermentation. Fermentation. 2024; 10(12):606. https://doi.org/10.3390/fermentation10120606