Chemical and Biological Characteristics of Ethanolic Extract of Tussilago
farfara L. Flowers: Composition, Antimicrobial and Antioxidant Activities
D. TERENZHEV1, N. SHARONOVA1,*, A. ERMAKOVA1, S. GUMEROVA1, K. BUSHMELEVA1, G. SHUMATBAEV1, I. FITSEV2 and A.S. PONOMAREVA3
1Laboratory for Plant Raw Material Conversion for Organic Farming, Federal State Budgetary Institution of Science Federal Research Center,
Kazan Scientific Center of Russian Academy of Sciences, 2/31 Lobachevskogo Ul., Kazan 420111, Russia
2Distributed Spectral-Analytical Center of Shared Facilities for Study of Structure, Composition and Properties of Substances and Materials,
Federal State Budgetary Institution of Science Federal Research Center, Kazan Scientific Center of Russian Academy of Sciences, 2/31
Lobachevskogo Ul., Kazan 420111, Russia
3Pryanishnikov All Russian Scientific Research Institute of Agrochemistry, 31 A Pryanishnikova St, Moscow 127550, Russia
*Corresponding author: E-mail: sharonovanl1979@gmail.com
Received: 3 August 2019; Accepted: 21 September 2019; Published online: 16 November 2019; AJC-19656
Tussilago farfara L. (Asteraceae) has a wide spectrum of biological reactivity, widely used in herbal medicine and has the potential for use
in the agricultural sector. The ethanolic extract was obtained by maceration of freshly harvested flowers, followed by filtration of the
extract and concentration with the help of a rotary evaporator. The chemical composition of ethanolic extract of Tussilago farfara L. was
studied with the help of gas chromatography/mass spectrometry (GC/MS) method. It was found that the ethanolic extract of Tussilago farfara
L. had antimicrobial reactivity against human pathogens and phytopathogens (bacteria and fungi). The values of the minimal inhibiting,
bactericidal and fungicidal concentrations varied in the range of 2500-5000 μg/mL. The phytopathogenic fungus Alternaria solani St108
was the most sensitive to the components of ethanolic extract of Tussilago farfara L. Moderate antioxidant properties of ethanolic extract
of Tussilago farfara L. at concentrations of 0.001 mg/mL and higher were revealed with the help of chemiluminescence analysis.
Keywords: Tussilago farfara L., Ethanolic extract, Chemical compositions, Antimicrobial activity, Antioxidant activity.
