Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity

Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity

Вы просматриваете редакцию с названием "Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity", сохраненную 12.07.2021 в 19:44 в Амерханова (Гумерова) Сюмбеля Камилевна
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Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity
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Versatile approach to naphthoquinone phosphonium salts
and evaluation of their biological activity
Nadezhda R. Khasiyatullina,* Vladimir F. Mironov, Sumbel K. Gumerova,
Alexandra D. Voloshina and Anastasia S. Sapunova
A. E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian
Academy of Sciences, 420088 Kazan, Russian Federation. E-mail: nadya.ksu@mail.ru
DOI: 10.1016/j.mencom.2019.07.027

A new efficient method for the synthesis of 1,4-dihydroxy-
2‑naphthylmethyl- and 1,4-dioxo-2(1H,4H)-2-naphthylmethylphosphonium
salts by reactions of 2-methyl-1,4-naphthoquinone
with appropriate P–H-phosphonium trifluoroacetates
has been suggested. The reactions were carried out under mild
conditions and provided high yields of target compounds.
Representative reaction products have been found to possess
moderate antimicrobial
and antitumor activity.

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12.07.2021 в 16:44 Амерханова (Гумерова) Сюмбеля Камилевна

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